Vitamin D & COVID-19 Journal Article Review

This journal article was published in the Journal of Nutrition, Health, and Aging this month October 2020.


Here is a summary:


Article Title: Impact of Serum 25(OH) Vitamin D Level on Mortality in Patients with COVID-19 in Turkey


Study: Retrospective observational


Demographics: 149 COVID-19 patients. 47 patients (31.5%) had moderate COVID-19 and 102 patients (68.5%) had severe-critical COVID-19.


Vitamin D level: The average vitamin D level in 34 (22.8%) and 103 (69.1%) patients had vitamin D insufficiency and deficiency, respectively. Average vitamin D level was significantly lower in patients with severe-critical COVID-19 compared with moderate COVID-19.

Vitamin D insufficiency was present in 93.1% of the patients with severe-critical COVID-19.


Conclusion: Serum 25(OH) vitamin D was independently associated with mortality in COVID-19 patients.


Limitations: The study did not control all the factors that potentially might have impacted the mortality rate. The sample size is relatively small. They only included patients who had moderate-to-severe COVID-19.


Article recommends: Since COVID-19 it is still rampant in many areas of the world, and considering the lack of an effective vaccine and specific drugs, measures to strengthen the immune system might be strongly considered.


Mentioned benefits in article about vitamin D:

*important immune functions *beneficial anti-viral effect by enhancing physical barrier against the viruses *beneficial effects on innate and adaptive immunity supports the innate immune system by means of inducing the secretion of several antimicrobial peptides such as defensins has itself several virus suppressive effect


Link to Article: https://link.springer.com/.../10.1007/s12603-020-1479-0...

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